Using a contactor to block miswiring in a test setup

Hi,

My question is, is it possible to use a contactor to block a miswiring between two voltage sources,as one is very low (5VDC) and one is high (500VDC), miswiring of course causes catastrophic damage to the electronics, I have a basic fix in place that should keep errors to a minimum, but I would like to avoid them altogether, so is there a way to set up something that if the wrong voltage is applied to the terminal that it would not allow it to pass?
 
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